代表性论文:(*为通讯作者) 1. Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B. (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37: 911-924. 2. Nishimura I, Yang Y, Lu B. (2004) PAR-1 kinase plays an initiator role in a multisite sequential phosphorylation process that confers Tau neurotoxicity in Drosophila CELL 116: 671. 3. Yang Y, Gehrke S, Haque M E, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S. Lu B(2005) Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci USA 102: 13670-13675. 4. Kumar S, Wen X, Yang Y, Buckmaster P. (2006) GABAA receptor-mediated IPSCs and α1 subunit expression are not reduced in the substantia nigra pars reticulata of gerbils with inherited epilepsy. J Neurophysiol 95: 2446. 5. Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, Vogel H, Lu B. (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci USA 103: 10793-10798. 6. Yang Y, Ouyang L,Yang MF, Beal A, McQuibban H, Vogel B, Lu B. (2008) Pink1 regulates mitochondrial dynamics through interaction with fission/fusion machinery Proc Natl Acad Sci USA105:7070-75. 7. Yang Y*, Lu B. (2009) Mitochondrial morphogenesis, distribution and Parkinson’s disease: insights from PINK1 J Neuropathology Exp Neurology 68: 953-963. 8. Faust K, Gehrke S, Yang Y, Yang L, Beal MF, Lu B. (2009) Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease. BMC Neurosciences 10:109. 10. Zhicao Yue, Ailing Huang, Yufeng Yang* Screening of neuroprotective compounds using multiple Drosophila models of Parkinson's disease Chinese Journal of Biochemistry and Molecular Biology, 2010.02.20,26(2):128~133 11. Yan Liu, Jingjing Lin , Minjie Zhang, Kai Chen, Shengxi Yang, Qun Wang, Xi Zhang, Fei Chen , Yufeng Yang* PINK1 Is Required for Timely Cell-Type Specific Mitochondrial Clearance During Drosophila Midgut Metamorphosis Developmental Biology,2016.08.26,419(2):357~372 12. Wenfeng Chen, Guosheng Lin, Yizhou Yao , et al. Yufeng Yang * and Yongjian Zhou MicroRNA hsa-let-7e-5p as a potential prognosis marker for rectal carcinoma with liver metastases Oncology Letters 15: 6913-6924, 2018 13. YUFENG YANG*: MAPK信号通路抑制剂在制备延缓多巴胺能神经元退化的药物中的应用专利PCT/CN2016/102154 |