已发表论文:(*为通讯作者) (1) 余凌奇, 谢甲钰, 原垚, 凌圣安, 陈文锋(*).利用果蝇模型研究人类II型腓骨肌萎缩症的进展. 中国细胞生物学学报, 2023, 45(1): 122-132. (2) Huang Y; Wen DJ; Yuan, Y; Chen WF(*). Gene Set Enrichment Analysis and Genetic Experiment Reveal Changes in Cell Signaling Pathways Induced by α-Synuclein Overexpression. Biomedicines, 2023, 11,263. (3) Wang DF, Chen J, Yuan Y, Yu LQ, Yang G(*), Chen WF(*).CRISPR/Cas9-mediated knockout of period reveals its function in the circadian rhythms of the diamondback moth Plutella xylostella. Insect Science, 2022, doi: 10.1111/1744-7917.13139. (4) Du XY(#), Yu LQ(#), Ling SA, Xie JY, Chen WF(*). High-salt diet impairs the neurons plasticity and the neurotransmitters-related biological processes. Nutrients, 2021, 13, 4123. (5) Wang DF, Yang G(*), Chen WF(*). Diel and circadian patterns of locomotor activity in the adults of diamondback moth (Plutella xylostella). Insects, 2021, 12, 727. (6) Chen WF(#), Liu ZX(#), Li TJ, Zhang RF, Xue Y, Zhong Y, Bai WW, Zhou DS, Zhao ZW(*).Regulation of Drosophila circadian rhythms by miRNA let-7 is mediated by a regulatory cycle. Nature Communications, 2014, 5: 5549. doi:10.1038/ncomms6549. (7) Lin JJ(#), Chen K(#), Chen WF(#), Yao YZ(#), Ni SW(#), Ye MN, Zhuang GF, Hu MH, Gao J, Gao CX, Liu Y, Yang MJ, Zhang ZK, Zhang XH, Huang JX, Chen F, Sun L, Zhang X, Yu SH, Chen YL, Jiang YT, Wang SJ, Yang XZ, Liu K, Zhou HM, Ji ZL, Deng HT, Haque ME, Li JX, Mi LZ, Li YX(*), Yang YF(*). Paradoxical mitophagy regulation by PINK1 and TUFm. Molecular Cell, 2020, 80: 1-14. (8) He XZ(#), Chen WF(#), Liu Z #, Yu GR, Chen YB, Cai YJ, Sun L, Xu WL, Zhong LL, Gao CX, Chen JS, Zhang MJ, Yang SX, Yao YZ, Zhang ZP, Ma FJ, Zhang CC, Lu HP, Yu B, Cheng TL, Qiu JH, Sheng Q, Zhou HM, Lv ZR, Yan JJ, Zhou YJ, Qiu ZL, Cui ZB, Zhang X, Meng AM, Sun Q(*), Yang YF(*). Efficient and risk-reduced genome editing using double nicks enhanced by bacterial recombination factors in multiple species. Nucleic Acids Research,2020,doi: 10.1093/nar/gkaa195 (9) Sun L(#), Zhang J(#), Chen WF(#), Chen Y, Zhang XH, Yang MJ, Ma FJ, Yao YZ, Ye MN, Zhang ZK, Chen K, Chen F, Ren YJ, Ni SW, Zhang X, Yan ZM, Sun ZR, Zhou HM, Yang HQ, Xie SS, Haque ME, Huang K*, Yang YF*. Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. Aging Cell, 2020, 19: e13210. (10) Xie JY, Wang DF, Ling SA, Yang G, Yang YF, Chen WF(*). High-salt diet causes sleep fragmentation in young Drosophila through circadian rhythm and dopaminergic systems. Frontiers in Neuroscience, 2019, 13: 1271. doi: 10.3389/fnins.2019.01271. (11) Chen WF, Xue YB, Scarfe L, Wang DF, Zhang Y(*). Loss of prune in circadian cells decreases the amplitude of the circadian locomotor rhythm in Drosophila. Frontiers in Cellular Neuroscience, 2019, 13:76. doi: 10.3389/fncel.2019.00076. (12) Chen WF, Werdann M, Zhang Y(*). The auxin-inducible degradation system enables conditional PERIOD protein depletion in the nervous system of Drosophila melanogaster. FEBS Journal, 2018, 285(23): 4378-4393. (13) Chen WF, Lin GS, Yao YZ, Chen JS, Shui HL, Yang QH, Wang XY, Weng XY, Sun L, Chen F, Yang S, Yang YF(*), Zhou YJ(*). MicroRNA has-let-7e-5p as a potential prognosis marker for rectal carcinoma with liver metastases. Oncology Letters, 2018, 15: 6913-6924. (14) Chen WF,Shi W,Li LZ,Zheng Z,Li TJ,Bai WW,Zhao ZW(*). Regulation of sleep by the short neuropeptide F(sNPF) in Drosophila melanogaster. Insect Biochemistry and Molecular Biology, 2013, 43: 809-819. (15) Nian XG, Chen WF, Bai WW, Zhao ZW, Zhang Y(*). MiR-263b controls circadian behavior and the structural plasticity of pacemaker neurons by regulating the LIM-only protein Beadex. Cells, 2019, 8, 923. (16) Nian XG(#), Chen WF(#), Bai WW, Zhao ZW(*). Regulation of circadian locomotor rhythm by miR-263a. Biological Rhythm Research, 2020, DOI:10.1080/09291016.2020.1726049. (17) Khair SBA, Dhanushkodi NR, Ardah MT, Chen WF, Yang YF, Haque ME(*). Silencing of glucocerebrosidase gene in Drosophila enhances the aggregation of Parkinson’s disease associated a-Synuclein mutant A53T and affect locomotor activity. Frontiers in Neuroscience, 2018, 12: 81. (18) He J, Guo LL, Lin S., Chen WF, Xu GR, Cai B, Xu LQ, Hong JM, Qiu LL, Wang N, and Chen WJ(*). ATP1A1 mutations cause intermediate Charcot-Marie-Tooth disease. Human Mutations, 2019, 40, 2334-2343. (19) 张敏杰,孙玲,刘真,蔡毅君,孙强,杨宇丰,陈文锋(*). 可编辑核酸酶介导的哺乳动物基因敲入技术最新进展. 中国细胞生物学学报, 2016, 38: 1-9. (通讯作者) (20) 陈文锋(*),王丹凤,黄少康. 蜜蜂生物节律的研究进展. 科技导报,2019, 37(6): 98-103. (第一作者和通讯作者) (21) 王丹凤,杨广,陈文锋(*). 微小RNA和长链非编码RNA介导的生物节律调控研究进展. 昆虫学报,2019, 62(6): 769-778. (通讯作者) (22) 陈文锋(*),谢甲钰,王丹凤,杨广(*).蚤蝇的昼夜活动节律及睡眠行为研究. 环境昆虫学报,2019,41(3): 435-442. (第一作者和通讯作者) (23) 谢甲钰,王丹凤,陈文锋(*). 黑腹果蝇头部响应高盐摄入的基因可变剪接分析. 环境昆虫学报,2019, 41(6): 1329-1338. (通讯作者) (24) 谢甲钰,王丹凤,陈文锋(*).基因集富集分析探讨帕金森病和癌症致病基因DJ-1的潜在功能.基因组学与应用生学, 2020, (39): 5278-5285. (通讯作者) (25) 王丹凤,谢甲钰,杨广(*),陈文锋(*). 谷氨酸钠摄入引起的果蝇肠道菌群多样性变化研究. 环境昆虫学报,2021, 43(1): 170-180. (共同通讯作者) (26) 陈文锋, 贺春霞, 安春菊, 赵章武(*). 昆虫生物钟分子调控研究进展. 应用昆虫学报, 2011 授权发明专利: (1) 发明人:陈文锋. 一种轴突型腓骨肌萎缩症果蝇模型的构建方法及应用. 授权号:202010311611.3, 授权日期:20211228, 专利权人: 福州大学 (2) 发明人: 陈文锋, 杨宇丰, 孙玲. 一种猴子早期胚胎转基因敲入的PCR鉴定方法. 授权号:CN105816461A, 授权日期:20190312, 专利权人: 福州大学 (3) 发明人:杨宇丰, 黄昆, 张洁, 张西, 孙玲, 陈文锋, 倪世伟, 陈云. U0126在制备治疗帕金森药物上的应用. 授权号:CN105796543A, 授权日期:20181030, 专利权人: 福州大学 (4) 发明人:杨宇丰, 张西, 孙玲, 陈文锋, 倪世伟. PD0325901在制备治疗帕金森药物上的应用. 授权号:CN105796537A, 授权日期:20181030, 专利权人: 福州大学 (5) 发明人:杨宇丰, 张西, 孙玲, 陈文锋, 倪世伟. 曲美替尼在制备治疗帕金森症药物上的应用. 授权号:CN105816461A, 授权日期:20181030, 专利权人: 福州大学 |